The latest basic science on Alzheimer's: proteins, cellular mechanisms, genetics research, and institutional findings.
151 articles found
A rare combination of lifelong cognitive tracking, postmortem brain analysis, and targeted mouse experiments reveals unexpected changes in the cells that maintain the brain’s white matter. A recent s...
By tracking every identified former NFL player who died over 14 years and examining hundreds of donated brains, researchers sought to overcome a long-standing challenge in estimating the true burden o...
A new review revisits the J-shaped curve, wine polyphenols, cancer risk, and the modeling choices behind increasingly restrictive alcohol guidelines. Review: Interpreting the Evidence on Wine Consump...
During typical aging and Alzheimer's disease progression, higher levels of a protein called tau are associated with more depressive symptoms. New in JNeurosci, Teodora Markova, from Brandeis Universit...
People who speak more than one language may have brains that appear younger than expected for their age, according to research presented at the Federation of European Neuroscience Societies (FENS) For...
A review and opinion piece published in The Lancet and led by UCL (University College London) and UCLH researchers discusses the possibility that blood transfusions may inadvertently transmit harmful ...
Researchers at Washington University School of Medicine in St. Louis have discovered lymph node-like structures in the skull bone marrow of mice for the first time and demonstrated that they act as ra...
Re:Cognition Health, the UK's largest independent provider of Alzheimer's disease-modifying treatments, announces the opening of its first Irish clinic in Dublin, marking a major milestone in dementia...
Ursula Quitterer calls it "Compound 10," a chemical substance developed by her research team that could potentially slow the progression of Alzheimer's disease. Quitterer, Professor of Molecular Phar...
Researchers at The Icahn School of Medicine at Mount Sinai have identified a role for the youth-associated protein TIMP2 in supporting the healthy function of microglia, the brain's resident immune ce...
For decades, scientists have generally viewed the brain's immune system as largely separate from the immune defenses operating throughout the rest of the body. The brain has its own specialized immune...
Research has shown that a good night's sleep has many benefits, including memory consolidation. How sleep enables the brain to strengthen memories is still not completely understood, but a new study p...
Research from scientists at University of California San Diego School of Medicine and collaborators has shed new light on how the human brain coordinates working memory, the process in which the brain...
University of Houston College of Pharmacy researchers have secured more than $1 million in new funding to support three separate studies targeting sepsis, Alzheimer's disease and related dementias, an...
Brain-resident immune cells that have reached an old-age state called "senescence" secrete a protein that causes dysfunction in other brain cells, according to a study led by investigators at Weill Co...
Researchers at University of California San Diego and their colleagues have identified a key cellular pathway that drives brain degeneration in both a rare childhood disorder and the far more common A...
Women live longer than men in nearly every country in the world, yet they experience higher rates of disability, dementia and many other age-related conditions. Scientists have long noted these differ...
A growing understanding of RNA biology is reshaping how scientists view the relationship between environmental toxicants, brain development, and neurodegenerative disease. A new review highlights the ...
A study funded by the National Institutes of Health (NIH) has uncovered a major shift in the immune environment of the hippocampus, the part of the brain that plays a central role in learning and memo...
Researchers from the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC have found that depression is associated with smaller volume i...
Maria Glymour, Andrew Stokes, and Deborah Carr will lead the Boston University-Quantitative Population Science and Healthy Cognitive Aging Research Program (BU-SHARP) to foster national research colla...
It may seem natural to assume that people experience cognitive decline after age 90, but until recently, researchers had limited evidence about how advanced age affects the brain. This major knowledge...
How can Alzheimer's research be made faster, better, and more effective? After decades of intensive research worldwide and despite recent therapeutic advances, scientists have not managed to fully arr...
Hallucinations and delusions that appear for the first time in midlife or later are often treated as psychiatric symptoms whose biological cause is unclear. The study, published online in Molecular Ps...