Blood tests, screening tools, biomarkers, and AI-assisted diagnostic advances for Alzheimer's and dementia.
48 articles found
In people diagnosed with early-onset Alzheimer's disease, a biomarker tool that detects shrinkage of the brain's gray matter may predict how quickly someone may progress from mild cognitive impairment...
Alzheimer's disease (AD) accounts for 60–80% of global dementia cases, with its core pathological feature being the misfolding and aggregation of β-amyloid (Aβ) proteins in the brain. These misfolded ...
The U.S. Food and Drug Administration (FDA) has cleared for marketing an innovative blood test with underlying technology invented at Washington University School of Medicine in St. Louis for the earl...
A new study suggests that Alzheimer's disease may be detected by brain imaging more than seven years earlier than previously assumed. Researchers from the Department of Psychology at the University of...
AI-based "tissue clocks" can estimate the biological age of human organs from histological images, researchers at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences an...
Researchers have identified seven proteins in the blood that could enable better blood tests for Alzheimer's disease. A study shows that using a broader panel of markers provides a clearer picture of ...
Alter Dementia, Dementia Care Aware (DCA) and SageNavigator facilitated more than 100 free, community-based cognitive screenings at the 2026 Alter Dementia Summit and Aging Well Expo in Atlanta, Georg...
Alzheimer's disease has traditionally been studied as a condition that primarily affects the brain's gray matter, where neuronal cell bodies are located and some of the disease's most characteristic l...
USC researchers have developed an approach that uses artificial intelligence to generate detailed maps that highlight differences in how distinct parts of the brain age. The new model also sheds light...
New blood tests that detect early changes associated with Alzheimer's disease are making diagnosis easier and accessible to more patients, since they are less invasive than the brain scans or spinal t...
Widely used Alzheimer’s biomarker P-tau 217 reliably detects the disease only at the clinical stage. The protein misfolding of amyloid beta indicates an increased risk years earlier. The misfolding o...
A six-cohort analysis links higher baseline p-tau217 to rising 5- and 10-year risks, bringing presymptomatic risk models closer while showing why routine screening is not yet ready. Study: Prognostic...
Regularly sleeping long hours each night is associated with higher levels of an Alzheimer's-related protein in the blood, even accounting for other health factors, suggests a new study from UT Health ...
A blood test for the biomarker phosphorylated tau 217 (p-tau217) recently received federal clearance, but questions have emerged around the extent to which such tests can accurately predict whether a ...
A small wireless patch captured water-sensitive brain signals through natural sleep, opening a potential path to home-based research into how sleep stages shape brain-fluid dynamics. Study: A soft we...
A blood-based circRNA signature could help identify early Alzheimer’s biology and progression risk, offering a promising new layer beyond amyloid and tau testing. Study: Blood-based circular RNAs for...
Cognitive decline in very old adults has been considered for decades to be an almost inevitable consequence of aging. In clinical practice, this has contributed to many memory problems in patients ove...
A blood test does not lie, exactly. It reports a number. The question raised by a new mini-review in Brain Medicine, which gathers and weighs a decade of scattered findings, is whether clinicians have...
A large plasma proteomics study shows that aging patterns in specific cell types may help identify who is more vulnerable to disease and who is more resilient. Study: Plasma proteomic signatures of c...
Often called "the window to the soul," the eyes may also offer clues about something less poetic but just as important: the health of the brain. A new study of tens of thousands of patients revealed ...
The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others. Whoever put the candles on your cake ...
Alzheimer's disease and related dementias are expected to more than double by 2060. As June marks Alzheimer's and Brain Awareness Month, three University of Florida researchers are working to improve ...
A new brain imaging test can detect a key hallmark of Alzheimer's disease before symptoms appear and earlier than the method currently used in clinical practice in the United States and Europe, report...
For the first time, researchers found blood biomarkers for Alzheimer's disease that correlated with minor cognitive differences in midlife adults who did not have dementia. The study, led by UC San Fr...