The full, searchable history of Alzheimer's and dementia research covered on this site.
324 articles found
In people diagnosed with early-onset Alzheimer's disease, a biomarker tool that detects shrinkage of the brain's gray matter may predict how quickly someone may progress from mild cognitive impairment...
Mass General Brigham Neuroscience Institute researchers have found that a pattern of brain atrophy visible on MRI could help predict how quickly people with early-onset Alzheimer's disease progress fr...
A rare combination of lifelong cognitive tracking, postmortem brain analysis, and targeted mouse experiments reveals unexpected changes in the cells that maintain the brain’s white matter. A recent s...
By tracking every identified former NFL player who died over 14 years and examining hundreds of donated brains, researchers sought to overcome a long-standing challenge in estimating the true burden o...
The adult human brain has limited capacity to repair or regenerate neurons lost to Alzheimer's disease, the most common type of dementia. Existing treatments can slow disease progression but do not re...
In a new study from Mass General Brigham, Boston University (BU), and the Concussion & CTE Foundation, researchers found evidence that at least 1-in-4 former NFL players who died between 2016 and 2021...
Alzheimer's disease (AD) accounts for 60–80% of global dementia cases, with its core pathological feature being the misfolding and aggregation of β-amyloid (Aβ) proteins in the brain. These misfolded ...
A new review revisits the J-shaped curve, wine polyphenols, cancer risk, and the modeling choices behind increasingly restrictive alcohol guidelines. Review: Interpreting the Evidence on Wine Consump...
A new framework traces the complex biological pathways linking food to brain health and asks why the same dietary pattern may not work equally for everyone. Diet as a modifiable risk factor for Alzhe...
On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem like unrelated diseases. ALS destroys moto...
During typical aging and Alzheimer's disease progression, higher levels of a protein called tau are associated with more depressive symptoms. New in JNeurosci, Teodora Markova, from Brandeis Universit...
A new analysis of biological aging across the human body suggests that both sleeping too little and sleeping too much are associated with faster aging in the brain, heart, lungs, immune system, and ot...
Millions of people carry APOE4, the strongest known genetic risk factor for Alzheimer's disease. New research suggests the gene variant may begin altering brain activity well before memory problems be...
More than 7 million Americans are currently living with Alzheimer's dementia, and that number is expected to climb to nearly 13 million by 2050. New research from Emory University suggests that higher...
People who speak more than one language may have brains that appear younger than expected for their age, according to research presented at the Federation of European Neuroscience Societies (FENS) For...
The U.S. Food and Drug Administration (FDA) has cleared for marketing an innovative blood test with underlying technology invented at Washington University School of Medicine in St. Louis for the earl...
Understanding how molecular changes shape brain function and disease requires more than measuring genes in bulk tissue. The brain contains highly diverse cell populations organized into complex anatom...
A review and opinion piece published in The Lancet and led by UCL (University College London) and UCLH researchers discusses the possibility that blood transfusions may inadvertently transmit harmful ...
Researchers at Washington University School of Medicine in St. Louis have discovered lymph node-like structures in the skull bone marrow of mice for the first time and demonstrated that they act as ra...
Re:Cognition Health, the UK's largest independent provider of Alzheimer's disease-modifying treatments, announces the opening of its first Irish clinic in Dublin, marking a major milestone in dementia...
A new study suggests that Alzheimer's disease may be detected by brain imaging more than seven years earlier than previously assumed. Researchers from the Department of Psychology at the University of...
For years, scientists have known that regular physical activity can help lower the risk of dementia. But new USC research suggests that it's not only the amount but also the activity's context - for w...
Ursula Quitterer calls it "Compound 10," a chemical substance developed by her research team that could potentially slow the progression of Alzheimer's disease. Quitterer, Professor of Molecular Phar...
Physical activity and healthy blood sugar levels during midlife may be linked to a significantly slower decline in thinking abilities later in life, according to new research from UT Health San Antoni...