The full, searchable history of Alzheimer's and dementia research covered on this site.
26 articles found
Mass General Brigham Neuroscience Institute researchers have found that a pattern of brain atrophy visible on MRI could help predict how quickly people with early-onset Alzheimer's disease progress fr...
The adult human brain has limited capacity to repair or regenerate neurons lost to Alzheimer's disease, the most common type of dementia. Existing treatments can slow disease progression but do not re...
In a new study from Mass General Brigham, Boston University (BU), and the Concussion & CTE Foundation, researchers found evidence that at least 1-in-4 former NFL players who died between 2016 and 2021...
On the surface, amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD) and limbic-predominant age-related TDP-43 encephalopathy (LATE) might seem like unrelated diseases. ALS destroys moto...
Millions of people carry APOE4, the strongest known genetic risk factor for Alzheimer's disease. New research suggests the gene variant may begin altering brain activity well before memory problems be...
Understanding how molecular changes shape brain function and disease requires more than measuring genes in bulk tissue. The brain contains highly diverse cell populations organized into complex anatom...
Established Alzheimer's markers are also detected in blood samples from Nigeria and Tanzania. But other proteins in the blood differ from those seen in a comparable group in Canada. This is important ...
What if certain signs of the disease were to manifest themselves subtly during sleep, long before the first memory problems appear? This is the line of inquiry being explored by a team of researchers ...
Exceptional memory in later life may depend less on inherited Alzheimer's risk and more on the biological and lifestyle factors that help some older adults stay cognitively sharp for decades. Study: ...
Researchers from Carnegie Mellon University's School of Computer Science, the University of Pittsburgh School of Medicine and the University of Washington shed new light on Alzheimer's disease that co...
Researchers at Niigata University have conducted the first comprehensive reappraisal in nearly 30 years of the risk of Alzheimer's disease (AD) associated with APOE-e4 homozygosity (e4*4) in the Japan...
New research from Edith Cowan University (ECU) has discovered an important link between our genes and sleep habits, suggesting they work together to influence early brain and cognitive changes associa...
Researchers at the USC Mark and Mary Stevens Neuroimaging and Informatics Institute (Stevens INI) at the Keck School of Medicine of USC analyzed brain imaging and clinical data from more than 17,000 p...
In the coming weeks, the Human Genome and Stem Cell Research Center (HUG-CELL) will begin recruiting participants for the "Our Genes" project. The initiative aims to identify couples at an increased r...
When looking at genetic variants in a person's DNA that predispose them to disease, a new study has found having a higher number of genetic variants for increased pulse pressure is associated with a s...
A nationwide study finds that Black and Latinx adults with cognitive impairment are less likely to have Alzheimer’s-linked amyloid buildup, even as they face higher rates of dementia, raising urgent q...
Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome, the working portion of our DNA that helps make each person uni...
DZNE researchers have generated new insights into how the human genome shapes the chemical composition and concentration of blood lipids. Across the genome, they identified more than 50 regions whose ...
Sleep complaints may be an important Alzheimer's disease risk factor in older women with a higher genetic predisposition to the disease, according to a new study from researchers at the University of ...
With a new $6.2 million, five-year grant from the National Institute on Aging, researchers at Case Western Reserve University will use artificial intelligence (AI) and machine learning to identify pos...
Scientists at the Buck Institute for Research on Aging, along with collaborators at UC San Francisco, have discovered that APOE4, the most common genetic risk factor for Alzheimer's disease, causes bo...
Gladstone Institutes investigator Ryan Corces, PhD, has been named a 2026 winner of the Pershing Square Foundation's MIND Prize, a prestigious award recognizing next-frontier thinkers who are uncoveri...
University of Virginia School of Medicine scientists have used a next-generation form of gene editing to fix the underlying cause of a severe form of epilepsy in lab mice. Their promising results sugg...
For more than four decades, in vitro fertilization (IVF) has helped families have children. Scientists estimate that more than 10 million people worldwide have been born through IVF and related assist...